Serotonin Nitric Oxide (Manduca sexta) Larvae Tobacco Hornworm Larvae Nitroxidergic neurons Sertontergic neurons muscular force development Muscle Dynamics Gut Immunohistochemistry Digestive System
The anterior mid-gut of the tobacco hornworm, Manduca sexta, is active in mixing freshly ingested diet with gut secretion. Spontaneous muscle activity is lost when the anterior gut is isolated, suggesting that neural and/or humoral inputs may be important in sustaining normal activity in vivo. In preliminary studies, both serotonin and cGMP (the putative second messenger for NO) were visualized in the anterior mid-gut by immunohistochemistry. We have also shown that serotonin and sodium nitroprusside (SNP), a NO donor, have measurable effects on the contractile state of isolated anterior gut. In these studies both serotonin and SNP caused a long-lasting contraction of longitudinal and circular muscle mounts.
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Title
Effects of Serotonin and Nitric Oxide on Mid-gut Motility in Tobacco Hornworm (Manduca sexta) Larvae
Creators
Evelia Sandoval (Author)
Contributors
David F Moffett (Other) - Washington State University, Biological Sciences, School of
Publication Details
WSU McNair Journal, Vol.1, pp.61-65
Academic Unit
McNair Journal
Publisher
Washington State University. Graduate School. McNair Program
Identifiers
99900502895501842
Copyright
In copyright ; openAccess ; http://rightsstatements.org/vocab/InC/1.0/ ; http://purl.org/eprint/accessRights/OpenAccess