Journal article
Elevated CO 2 impairs olfactory-mediated neural and behavioral responses and gene expression in ocean-phase coho salmon (Oncorhynchus kisutch)
Global change biology, Vol.25(3), pp.963-977
03/2019
Handle:
https://hdl.handle.net/2376/100708
PMID: 30561876
Abstract
Elevated concentrations of CO
in seawater can disrupt numerous sensory systems in marine fish. This is of particular concern for Pacific salmon because they rely on olfaction during all aspects of their life including during their homing migrations from the ocean back to their natal streams. We investigated the effects of elevated seawater CO
on coho salmon (Oncorhynchus kisutch) olfactory-mediated behavior, neural signaling, and gene expression within the peripheral and central olfactory system. Ocean-phase coho salmon were exposed to three levels of CO
, ranging from those currently found in ambient marine water to projected future levels. Juvenile coho salmon exposed to elevated CO
levels for 2 weeks no longer avoided a skin extract odor that elicited avoidance responses in coho salmon maintained in ambient CO
seawater. Exposure to these elevated CO
levels did not alter odor signaling in the olfactory epithelium, but did induce significant changes in signaling within the olfactory bulb. RNA-Seq analysis of olfactory tissues revealed extensive disruption in expression of genes involved in neuronal signaling within the olfactory bulb of salmon exposed to elevated CO
, with lesser impacts on gene expression in the olfactory rosettes. The disruption in olfactory bulb gene pathways included genes associated with GABA signaling and maintenance of ion balance within bulbar neurons. Our results indicate that ocean-phase coho salmon exposed to elevated CO
can experience significant behavioral impairments likely driven by alteration in higher-order neural signal processing within the olfactory bulb. Our study demonstrates that anadromous fish such as salmon may share a sensitivity to rising CO
levels with obligate marine species suggesting a more wide-scale ecological impact of ocean acidification.
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Details
- Title
- Elevated CO 2 impairs olfactory-mediated neural and behavioral responses and gene expression in ocean-phase coho salmon (Oncorhynchus kisutch)
- Creators
- Chase R Williams - Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WashingtonAndrew H Dittman - Environmental and Fisheries Sciences Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, Seattle, WashingtonPaul McElhany - Conservation Biology Division, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, Mukilteo, WashingtonD Shallin Busch - Ocean Acidification Program, Office of Oceanic and Atmospheric Research, National Oceanic and Atmospheric Administration, Seattle, WashingtonMichael T Maher - Conservation Biology Division, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, Mukilteo, WashingtonTheo K Bammler - Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WashingtonJames W MacDonald - Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WashingtonEvan P Gallagher - Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington
- Publication Details
- Global change biology, Vol.25(3), pp.963-977
- Academic Unit
- UNKNOWN
- Publisher
- England
- Grant note
- P42 ES004696 / NIEHS NIH HHS P42ES004696 / NIEHS NIH HHS
- Identifiers
- 99900546536601842
- Language
- English
- Resource Type
- Journal article