Journal article
Endothelins: New players in cardiovascular physiology and disease
The Journal of cardiovascular nursing, Vol.8(3), pp.87-104
04/1994
Handle:
https://hdl.handle.net/2376/104756
PMID: 8207462
Abstract
Intercellular signaling is an important factor in cardiovascular regulation and the development of disease. The endothelins (ETs) are a recently described family of signaling peptides that appear to be important in cardiovascular regulation. Initial studies showed ET to be a potent vasoconstrictor of vascular smooth muscle. Subsequently, ET binding and activity have been demonstrated in a wide variety of tissues, including cardiac, venular, adrenal, and neural. Numerous studies have implicated the ETs in cardiovascular diseases such as hypertension, heart failure, and atherosclerosis. This article briefly reviews ET signaling pathways and the roles ET may play in cardiovascular regulation and disease
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Details
- Title
- Endothelins: New players in cardiovascular physiology and disease
- Creators
- Jacquelyn Banasik - Associate Professor, Intercollegiate Center for Nursing, Education Spokane, Washington
- Publication Details
- The Journal of cardiovascular nursing, Vol.8(3), pp.87-104
- Academic Unit
- Nursing, College of
- Publisher
- Aspen Publishers, Inc
- Identifiers
- 99900547083501842
- Language
- English
- Resource Type
- Journal article