Journal article
Engineering Metal-Organic Framework-based Nanozymes for Enhanced Biosensing
Current analytical chemistry, Vol.18(6), pp.739-752
07/01/2022
Abstract
Background: Nanozymes are a kind of emerging nanomaterials that can mimic the catalytic activity of natural enzymes with good stability. Objective: Benefited by the unique coordination structure and constitution, metal-organic frameworks (MOFs) have been widely exploited as novel nanozymes. Importantly, various MOFs engineered with fascinating functions provide great opportunities to enhance their enzyme-like activity and improve their applied performance, achieving the goal of vividly mimicking natural enzymes. Conclusion: This review summarized recent advances in the fabrication of the MOFs-based nanozymes and their applications in biosensing. First, MOFs-based nanomaterials containing pristine MOFs, functionalized MOFs, MOFs-based composites and MOFs derivatives are introduced, where the design strategy, enzyme-like activity and the catalytic mechanisms are highlighted systematically. Then, their applications in various target assays are summarized. Finally, the challenges and possible research directions for the development and application of MOFs-based nanozymes are provided.
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Details
- Title
- Engineering Metal-Organic Framework-based Nanozymes for Enhanced Biosensing
- Creators
- Weiqing Xu - Central China Normal UniversityYu Wu - Central China Normal UniversityLei Jiao - Central China Normal UniversityWenling Gu - Central China Normal UniversityDan Du - Washington State UniversityYuehe Lin - Washington State UniversityChengzhou Zhu - Central China Normal University
- Publication Details
- Current analytical chemistry, Vol.18(6), pp.739-752
- Academic Unit
- School of Mechanical and Materials Engineering
- Publisher
- Bentham Science Publ Ltd
- Number of pages
- 14
- Grant note
- CCNU20QN007; CCNU20TS013 / Fundamental Research Funds for the Central Universities B17019 / Program of Introducing Talents of Discipline to Universities of China (111 program) 22074049; 22004042 / National Natural Science Foundation of China; National Natural Science Foundation of China (NSFC)
- Identifiers
- 99901227635901842
- Language
- English
- Resource Type
- Journal article