Journal article
Ephrin-A5 overexpression degrades topographic specificity in the mouse gluteus maximus muscle
Brain research. Developmental brain research, Vol.153(2), pp.271-274
2004
Handle:
https://hdl.handle.net/2376/107388
PMID: 15527895
Abstract
Motor neurons project onto specific muscles with a distinct positional bias. We have previously shown using electrophysiological techniques that overexpression of ephrin-A5 degrades this topographic map. Here, we show that positional differences in axon terminal areas, an entirely different parameter of neuromuscular topography, are also eliminated with ephrin-A5 overexpression. Therefore, we now have both morphological and electrophysiological approaches to explore the mechanisms of neuromuscular topography.
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Details
- Title
- Ephrin-A5 overexpression degrades topographic specificity in the mouse gluteus maximus muscle
- Creators
- S.J Lampa - Program in Neuroscience, Veterinary and Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman, WA 99164-6520, United StatesS Potluri - WWAMI Medical Program, University of Idaho, Moscow, ID 83844-4207, United StatesA.S Norton - WWAMI Medical Program, University of Idaho, Moscow, ID 83844-4207, United StatesW Fusco - Environmental Biotechnology Institute, University of Idaho, Moscow ID 83844-3006, United StatesM.B Laskowski - Program in Neuroscience, Veterinary and Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman, WA 99164-6520, United States
- Publication Details
- Brain research. Developmental brain research, Vol.153(2), pp.271-274
- Academic Unit
- Integrative Physiology and Neuroscience, Department of
- Publisher
- Elsevier B.V
- Identifiers
- 99900546827201842
- Language
- English
- Resource Type
- Journal article