Evidence for oxazepam as in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion

X I XI HE; Leah M HESSE; Suwagmani HAZARIKA; Gina MASSE; Jerold S HARMATZ; David J GREENBLATT; Michael H COURT

doi:10.1111/j.1365-2125.2009.03519.x

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Evidence for oxazepam as in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion

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Evidence for oxazepam as in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion

X I XI HE, Leah M HESSE, Suwagmani HAZARIKA, Gina MASSE, Jerold S HARMATZ, David J GREENBLATT and Michael H COURT

British journal of clinical pharmacology, Vol.68(5), pp.721-730

2009

DOI: https://doi.org/10.1111/j.1365-2125.2009.03519.x

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https://hdl.handle.net/2376/109157

PMCID: PMC2791978

PMID: 19916996

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Biological and medical sciences

Pharmacology. Drug treatments

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Title: Evidence for oxazepam as in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion
Creators: X I XI HE - Laboratory of Comparative and Molecular Pharmacogenomics and Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
Leah M HESSE - Laboratory of Comparative and Molecular Pharmacogenomics and Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
Suwagmani HAZARIKA - Laboratory of Comparative and Molecular Pharmacogenomics and Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
Gina MASSE - Laboratory of Comparative and Molecular Pharmacogenomics and Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
Jerold S HARMATZ - Laboratory of Comparative and Molecular Pharmacogenomics and Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
David J GREENBLATT - Laboratory of Comparative and Molecular Pharmacogenomics and Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
Michael H COURT - Laboratory of Comparative and Molecular Pharmacogenomics and Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA, United States
Publication Details: British journal of clinical pharmacology, Vol.68(5), pp.721-730
Academic Unit: Veterinary Clinical Sciences, Department of
Publisher: Blackwell; Oxford
Identifiers: 99900547362901842
Language: English
Resource Type: Journal article