Journal article
Evidence for δ-receptor involvement in the post-ictal antinociceptive responses to electroconvulsive shock in rats
Life sciences (1973), Vol.33(1), pp.583-585
1983
Handle:
https://hdl.handle.net/2376/113300
PMID: 6319914
Abstract
Studies were conducted with the putative δ-opioid receptor antagonist ICI 154,129 (ICI) and the putative δ-receptor antagonist β-funaltrexamine (β-FNA) to investigate their ability to block the acute opioid-like effects of a single electroconvulsive shock (ECS). ICI, but not β-FNA, attenuated the increase in hot-plate escape latencies seen following ECS. From these data, we conclude that ECS activates endogenous opioids which act upon δ rather than μ receptors to result in an increase in hot-plate escape latencies.
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Details
- Title
- Evidence for δ-receptor involvement in the post-ictal antinociceptive responses to electroconvulsive shock in rats
- Creators
- Gregory Lucas BelenkyDeborah Gelinas-SorellJulie R KennerJohn W Holaday
- Publication Details
- Life sciences (1973), Vol.33(1), pp.583-585
- Publisher
- Elsevier Inc
- Identifiers
- 99900547408301842
- Language
- English
- Resource Type
- Journal article