Journal article
Exercise and the endothelial cell
International journal of cardiology, Vol.99(2), pp.165-169
03/18/2005
Handle:
https://hdl.handle.net/2376/111095
PMID: 15749171
Abstract
Regular exercise is known to be effective in the prevention and treatment of cardiovascular disease. Among the cardioprotectant mechanisms influenced by exercise, the endothelium is becoming recognised as a major target. Preservation of endothelial cell structure is vital for frictionless blood flow, prevention of macrophage and lipid infiltration and, ultimately, optimal vascular function. Exercise causes various kinds of mechanical, chemical and thermal stresses, and repeated exposure to these stresses may precondition the endothelial cell to future stresses through a number of different mechanisms. This review discusses stress-induced changes in endothelial cell morphology, biochemistry and components of platelet activation and cell adhesion that impact on endothelial cell structure. An enhanced understanding of the effects of exercise on the endothelial cell will assist in directing future research into the prevention of cardiovascular disease.
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Details
- Title
- Exercise and the endothelial cell
- Creators
- Susan A Marsh - School of Human Movement Studies, The University of Queensland, Room 535 Connell Building, St. Lucia, Brisbane, Queensland 4072, AustraliaJeff S Coombes
- Publication Details
- International journal of cardiology, Vol.99(2), pp.165-169
- Academic Unit
- Pharmaceutical Sciences, Department of
- Publisher
- Netherlands
- Identifiers
- 99900547391601842
- Language
- English
- Resource Type
- Journal article