Journal article
Expressed sequence tags from life cycle stages of Trichinella spiralis: Application to biology and parasite control
Veterinary parasitology, Vol.132(1), pp.13-17
2005
Handle:
https://hdl.handle.net/2376/113605
PMID: 15993542
Abstract
While the approach taken to date to study
Trichinella spp., involves mainly characterization of individual genes of interest, we initiated a genomics approach as an antecedent to more complete genome sequencing. Our approach involves use of expressed sequence tags (ESTs) obtained from three life cycle stages of
Trichinella spiralis; adult worms (AD), mature muscle larvae (ML) and immature L1 larvae (immL1, also known as newborn larvae) (
Mitreva et al., 2004a) to improve the technical capacity for research on
Trichinella spp. and to generate information that will aid prospective development of relevant hypotheses. In this review, we will summarize findings of our EST analysis and discuss how they relate to topics mentioned above. The foundation laid by this data will also contribute toward development of a more substantial genomic database and technical capacity to dissect molecular interactions between vertebrate hosts and
Trichinella spp.
Metrics
6 Record Views
Details
- Title
- Expressed sequence tags from life cycle stages of Trichinella spiralis: Application to biology and parasite control
- Creators
- Makedonka Mitreva - Genome Sequencing Center, Department of Genetics, Washington University School of Medicine, 4444 Forest Park Boulevard, St. Louis, MO 63108, USAJudith Appleton - James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Hungerford Hill Road, Ithaca, NY 14853, USAJames P McCarter - Genome Sequencing Center, Department of Genetics, Washington University School of Medicine, 4444 Forest Park Boulevard, St. Louis, MO 63108, USADouglas P Jasmer - Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164-7040, USA
- Publication Details
- Veterinary parasitology, Vol.132(1), pp.13-17
- Academic Unit
- Veterinary Microbiology and Pathology, Department of
- Publisher
- Elsevier B.V
- Identifiers
- 99900547436501842
- Language
- English
- Resource Type
- Journal article