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Facile formation of dehydroalanine from S-nitrosocysteines
Journal article

Facile formation of dehydroalanine from S-nitrosocysteines

Hua Wang, Jiming Zhang and Ming Xian
Journal of the American Chemical Society, Vol.131(37), pp.13238-13239
09/23/2009
Handle:
https://hdl.handle.net/2376/107753
PMID: 19715315

Abstract

Alanine - analogs & derivatives Cysteine - analogs & derivatives Phosphines - chemistry S-Nitrosothiols - chemistry Alanine - chemistry Catalysis Cysteine - chemistry
A reductive elimination of S-nitrosocysteines using phosphine substrates has been developed. This reaction converts unstable S-nitrosocysteines to dehydroalanine derivatives under very mild conditions. It can potentially be applied for the detection of protein S-nitrosation.

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