Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race

Shunmugiah V Ramesh; Pranav P Sahu; Manoj Prasad; Shelly Praveen; Hanu R Pappu

doi:10.3390/v9090256

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Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race

Journal article

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Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race

Shunmugiah V Ramesh, Pranav P Sahu, Manoj Prasad, Shelly Praveen and Hanu R Pappu

Viruses, Vol.9(9), p.256

09/15/2017

DOI: https://doi.org/10.3390/v9090256

Handle:

https://hdl.handle.net/2376/110459

PMCID: PMC5618022

PMID: 28914771

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Abstract

Plants - virology

Viral Proteins - genetics

Genome, Plant

Viral Proteins - metabolism

Geminiviridae - genetics

Host-Pathogen Interactions

Plant Proteins - genetics

Plants - metabolism

Plant Diseases - virology

Plants - genetics

RNA Interference

RNA, Small Untranslated - genetics

Plant Proteins - metabolism

DNA, Single-Stranded

Genetic Vectors

DNA, Viral

Geminiviruses are plant-infecting viruses characterized by a single-stranded DNA (ssDNA) genome. Geminivirus-derived proteins are multifunctional and effective regulators in modulating the host cellular processes resulting in successful infection. Virus-host interactions result in changes in host gene expression patterns, reprogram plant signaling controls, disrupt central cellular metabolic pathways, impair plant's defense system, and effectively evade RNA silencing response leading to host susceptibility. This review summarizes what is known about the cellular processes in the continuing tug of war between geminiviruses and their plant hosts at the molecular level. In addition, implications for engineered resistance to geminivirus infection in the context of a greater understanding of the molecular processes are also discussed. Finally, the prospect of employing geminivirus-based vectors in plant genome engineering and the emergence of powerful genome editing tools to confer geminivirus resistance are highlighted to complete the perspective on geminivirus-plant molecular interactions.

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Title: Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race
Creators: Shunmugiah V Ramesh - Department of Plant Pathology, Washington State University, Pullman, WA 99163, USA. ramesh.sv@icar.gov.in
Pranav P Sahu - National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi110067, India. prnv_pankaj@yahoo.co.in
Manoj Prasad - National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi110067, India. manoj_prasad@nipgr.ac.in
Shelly Praveen - Division of Plant Pathology, Advanced Centre for Plant Virology, ICAR-Indian Agricultural Research Institute (IARI), New Delhi 110012, India. shellypraveen@hotmail.com
Hanu R Pappu - Department of Plant Pathology, Washington State University, Pullman, WA 99163, USA. hrp@wsu.edu
Publication Details: Viruses, Vol.9(9), p.256
Academic Unit: Plant Pathology, Department of
Publisher: Switzerland
Identifiers: 99900547285601842
Language: English
Resource Type: Journal article