Journal article
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994
eLife, Vol.5(2016), p.14
12/14/2016
Handle:
https://hdl.handle.net/2376/106516
PMCID: PMC5156525
PMID: 27964777
Abstract
Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886-1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0.69-0.84 in men and 0.53-0.78 in women) did not present any clear pattern of secular changes. Comparing geographic-cultural regions (Europe, North America and Australia, and East Asia), total height variance was greatest in North America and Australia and lowest in East Asia, but no clear pattern in the heritability estimates across the birth-year cohorts emerged. Our findings do not support the hypothesis that heritability of height is lower in populations with low living standards than in affluent populations, nor that heritability of height will increase within a population as living standards improve.
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- Title
- Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994
- Creators
- Aline Jelenkovic - Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country, Leioa, SpainYoon-Mi Hur - Department of Education, Mokpo National University, Jeonnam, South KoreaReijo Sund - Department of Social Research, University of Helsinki, Helsinki, FinlandYoshie Yokoyama - Department of Public Health Nursing, Osaka City University, Osaka, JapanSisira H Siribaddana - Faculty of Medicine & Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri LankaMatthew Hotopf - NIHR Mental Health Biomedical Research Centre, South London and Maudsley NHS Foundation Trust and, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, United KingdomAthula Sumathipala - Research Institute for Primary Care and Health Sciences, School for Primary Care Research, Faculty of Health, Keele University, Staffordshire, United KingdomFruhling Rijsdijk - MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United KingdomQihua Tan - Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, Odense, DenmarkDongfeng Zhang - Department of Public Health, Qingdao University Medical College, Qingdao, ChinaZengchang Pang - Department of Noncommunicable Diseases Prevention, Qingdao Centers for Disease Control and Prevention, Qingdao, ChinaSari Aaltonen - Department of Public Health, University of Helsinki, Helsinki, FinlandKauko Heikkilä - Department of Public Health, University of Helsinki, Helsinki, FinlandSevgi Y Öncel - Department of Statistics, Faculty of Arts and Sciences, Kirikkale University, Kirikkale, TurkeyFazil Aliev - Department of African American Studies, Virginia Commonwealth University, Richmond, United StatesEsther Rebato - Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country, Leioa, SpainAdam D Tarnoki - Hungarian Twin Registry, Budapest, HungaryDavid L Tarnoki - Hungarian Twin Registry, Budapest, HungaryKaare Christensen - Department of Clinical Genetics, Odense University Hospital, Odense, DenmarkAxel Skytthe - Department of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, DenmarkKirsten O Kyvik - Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, DenmarkJudy L Silberg - Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United StatesLindon J Eaves - Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United StatesHermine H Maes - Department of Human and Molecular Genetics, Psychiatry & Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United StatesTessa L Cutler - The Australian Twin Registry, Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, AustraliaJohn L Hopper - Department of Epidemiology, School of Public Health, Seoul National University, Seoul, KoreaJuan R Ordoñana - IMIB-Arrixaca, Murcia, SpainJuan F Sánchez-Romera - Department of Developmental and Educational Psychology, University of Murcia, Murcia, SpainLucia Colodro-Conde - QIMR Berghofer Medical Research Institute, Brisbane, AustraliaWendy Cozen - USC Norris Comprehensive Cancer Center, Los Angeles, United StatesAmie E Hwang - Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, United StatesThomas M Mack - USC Norris Comprehensive Cancer Center, Los Angeles, United StatesJoohon Sung - Institute of Health and Environment, Seoul National University, Seoul, South-KoreaYun-Mi Song - Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South-KoreaSarah Yang - Institute of Health and Environment, Seoul National University, Seoul, South-KoreaKayoung Lee - Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, KoreaCarol E Franz - Department of Psychiatry, University of California, San Diego, San Diego, United StatesWilliam S Kremen - VA San Diego Center of Excellence for Stress and Mental Health, La Jolla, CA, United StatesMichael J Lyons - Department of Psychology, Boston University, Boston, United StatesAndreas Busjahn - HealthTwiSt GmbH, Berlin, GermanyTracy L Nelson - Department of Health and Exercise Sciences and Colorado School of Public Health, Colorado State University, Colorado, United StatesKeith E Whitfield - Psychology and Neuroscience, Duke University, Durham, United StatesChristian Kandler - Department of Psychology, Bielefeld University, Bielefeld, GermanyKerry L Jang - Department of Psychiatry, University of British Columbia, Vancouver, CanadaMargaret Gatz - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenDavid A Butler - Health and Medicine Division, The National Academies of Sciences, Engineering, and Medicine, Washington, United StatesMaria A Stazi - Istituto Superiore di Sanità - National Center for Epidemiology, Surveillance and Health Promotion, Rome, ItalyCorrado Fagnani - Istituto Superiore di Sanità - National Center for Epidemiology, Surveillance and Health Promotion, Rome, ItalyCristina D'Ippolito - Istituto Superiore di Sanità - National Center for Epidemiology, Surveillance and Health Promotion, Rome, ItalyGlen E Duncan - Washington State Twin Registry, Washington State University - Health Sciences Spokane, Spokane, United StatesDedra Buchwald - Washington State Twin Registry, Washington State University, Seattle, United StatesCatherine A Derom - Department of Obstetrics and Gynaecology, Ghent University Hospitals, Ghent, BelgiumRobert F Vlietinck - Centre of Human Genetics, University Hospitals Leuven, Leuven, BelgiumRuth Jf Loos - The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, United StatesNicholas G Martin - Genetic Epidemiology Department, QIMR Berghofer Medical Research Institute, Brisbane, AustraliaSarah E Medland - Genetic Epidemiology Department, QIMR Berghofer Medical Research Institute, Brisbane, AustraliaGrant W Montgomery - Molecular Epidemiology Department, QIMR Berghofer Medical Research Institute, Brisbane, AustraliaHoe-Uk Jeong - Department of Education, Mokpo National University, Jeonnam, South KoreaGary E Swan - Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, United StatesRuth Krasnow - Center for Health Sciences, SRI International, Menlo Park, United StatesPatrik Ke Magnusson - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenNancy L Pedersen - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenAnna K Dahl-Aslan - Institute of Gerontology and Aging Research Network - Jönköping (ARN-J), School of Health and Welfare, Jönköping University, Jönköping, SwedenTom A McAdams - MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United KingdomThalia C Eley - MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United KingdomAlice M Gregory - Department of Psychology, Goldsmiths, University of London, London, United KingdomPer Tynelius - Department of Public Health Sciences, Karolinska Institutet, Stockholm, SwedenLaura A Baker - Department of Psychology, University of Southern California, Los Angeles, United StatesCatherine Tuvblad - School of Law, Psychology and Social Work, Örebro University, Örebro, SwedenGombojav Bayasgalan - Healthy Twin Association of Mongolia, Ulaanbaatar, MongoliaDanshiitsoodol Narandalai - Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, JapanPaul Lichtenstein - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenTimothy D Spector - Department of Twin Research and Genetic Epidemiology, King's College, London, United KingdomMassimo Mangino - Department of Twin Research and Genetic Epidemiology, King's College, London, United KingdomGenevieve Lachance - Department of Twin Research and Genetic Epidemiology, King's College, London, United KingdomMeike Bartels - Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsToos Cem van Beijsterveldt - Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsGonneke Willemsen - Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsS Alexandra Burt - Michigan State University, East Lansing, Michigan, United StatesKelly L Klump - Michigan State University, East Lansing, Michigan, United StatesJennifer R Harris - Norwegian Institute of Public Health, Oslo, NorwayIngunn Brandt - Norwegian Institute of Public Health, Oslo, NorwayThomas Sevenius Nilsen - Norwegian Institute of Public Health, Oslo, NorwayRobert F Krueger - Department of Psychology, University of Minnesota, Minneapolis, United StatesMatt McGue - Department of Psychology, University of Minnesota, Minneapolis, United StatesShandell Pahlen - Department of Psychology, University of Minnesota, Minneapolis, United StatesRobin P Corley - Institute for Behavioral Genetics, University of Colorado, Boulder, United StatesJacob V B Hjelmborg - Department of Public Health, Epidemiology, Biostatistics & Biodemography, University of Southern Denmark, Odense, DenmarkJack H Goldberg - Department of Epidemiology, School of Public Health, University of Washington, Seattle, United StatesYoshinori Iwatani - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanMikio Watanabe - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanChika Honda - Osaka University Graduate School of Medicine, Osaka University, Osaka, JapanFujio Inui - Faculty of Health Science, Kio University, Nara, JapanFinn Rasmussen - Department of Public Health Sciences, Karolinska Institutet, Stockholm, SwedenBrooke M Huibregtse - Institute for Behavioral Genetics, University of Colorado, Boulder, United StatesDorret I Boomsma - Department of Biological Psychology, VU University Amsterdam, Amsterdam, NetherlandsThorkild I A Sørensen - Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, Copenhagen, DenmarkJaakko Kaprio - Institute for Molecular Medicine FIMM, Helsinki, FinlandKarri Silventoinen - Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan
- Publication Details
- eLife, Vol.5(2016), p.14
- Academic Unit
- Community Health; Nutrition and Exercise Physiology, Department of
- Publisher
- England
- Grant note
- T32 DA017637 / NIDA NIH HHS R01 HD010333 / NICHD NIH HHS R21 AG039572 / NIA NIH HHS P01 AG008761 / NIA NIH HHS R01 AG022381 / NIA NIH HHS R01 ES015150 / NIEHS NIH HHS R03 MH063851 / NIMH NIH HHS R01 AG050595 / NIA NIH HHS R01 AG022982 / NIA NIH HHS R01 MH092377 / NIMH NIH HHS P60 DA011015 / NIDA NIH HHS R01 HD066040 / NICHD NIH HHS R21 MH070542 / NIMH NIH HHS R01 AA012502 / NIAAA NIH HHS R37 AA012502 / NIAAA NIH HHS R01 MH058354 / NIMH NIH HHS R01 AA009203 / NIAAA NIH HHS P30 AG017265 / NIA NIH HHS R01 MH081813 / NIMH NIH HHS R01 AG018386 / NIA NIH HHS K05 AA000145 / NIAAA NIH HHS R01 AG018384 / NIA NIH HHS 230374 / European Research Council RC2 HL103416 / NHLBI NIH HHS
- Identifiers
- 99900546985501842
- Language
- English
- Resource Type
- Journal article