Journal article
Genome-wide association studies dissect the genetic networks underlying agronomical traits in soybean
Genome biology, Vol.18(1), pp.161-161
08/24/2017
Handle:
https://hdl.handle.net/2376/114913
PMCID: PMC5571659
PMID: 28838319
Abstract
Soybean (Glycine max [L.] Merr.) is one of the most important oil and protein crops. Ever-increasing soybean consumption necessitates the improvement of varieties for more efficient production. However, both correlations among different traits and genetic interactions among genes that affect a single trait pose a challenge to soybean breeding.
To understand the genetic networks underlying phenotypic correlations, we collected 809 soybean accessions worldwide and phenotyped them for two years at three locations for 84 agronomic traits. Genome-wide association studies identified 245 significant genetic loci, among which 95 genetically interacted with other loci. We determined that 14 oil synthesis-related genes are responsible for fatty acid accumulation in soybean and function in line with an additive model. Network analyses demonstrated that 51 traits could be linked through the linkage disequilibrium of 115 associated loci and these links reflect phenotypic correlations. We revealed that 23 loci, including the known Dt1, E2, E1, Ln, Dt2, Fan, and Fap loci, as well as 16 undefined associated loci, have pleiotropic effects on different traits.
This study provides insights into the genetic correlation among complex traits and will facilitate future soybean functional studies and breeding through molecular design.
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Details
- Title
- Genome-wide association studies dissect the genetic networks underlying agronomical traits in soybean
- Creators
- Chao Fang - University of Chinese Academy of Sciences, Beijing, 100039, ChinaYanming Ma - State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaShiwen Wu - State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaZhi Liu - University of Chinese Academy of Sciences, Beijing, 100039, ChinaZheng Wang - State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaRui Yang - State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaGuanghui Hu - Institute of maize research, Heilongjiang Academy of Agricultural Sciences, Harbin, 150086, ChinaZhengkui Zhou - Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, ChinaHong Yu - State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaMin Zhang - State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaYi Pan - State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaGuoan Zhou - State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaHaixiang Ren - Mudanjiang Branch of Heilongjiang Academy of Agricultural Sciences, Mudanjiang, 157041, ChinaWeiguang Du - Institute of Soybean Research, Heilongjiang Academy of Agricultural Sciences, Harbin, 150086, ChinaHongrui Yan - Heihe Branch of Heilongjiang Academy of Agricultural Sciences, Heihe, 164300, ChinaYanping Wang - Mudanjiang Branch of Heilongjiang Academy of Agricultural Sciences, Mudanjiang, 157041, ChinaDezhi Han - Institute of Soybean Research, Heilongjiang Academy of Agricultural Sciences, Harbin, 150086, ChinaYanting Shen - University of Chinese Academy of Sciences, Beijing, 100039, ChinaShulin Liu - University of Chinese Academy of Sciences, Beijing, 100039, ChinaTengfei Liu - University of Chinese Academy of Sciences, Beijing, 100039, ChinaJixiang Zhang - University of Chinese Academy of Sciences, Beijing, 100039, ChinaHao Qin - State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaJia Yuan - State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaXiaohui Yuan - School of Computer Science and Technology, Wuhan University of Technology, Wuhan, 430070, ChinaFanjiang Kong - Key Laboratory of Soybean Molecular Design Breeding, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin, 130102, ChinaBaohui Liu - Key Laboratory of Soybean Molecular Design Breeding, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin, 130102, ChinaJiayang Li - State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, ChinaZhiwu Zhang - Department of Crop and Soil Sciences, Washington State University, Pullman, WA, 99164, USA. zhiwu.zhang@wsu.eduGuodong Wang - University of Chinese Academy of Sciences, Beijing, 100039, China. gdwang@genetics.ac.cnBaoge Zhu - State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China. bgzhu@genetics.ac.cnZhixi Tian - University of Chinese Academy of Sciences, Beijing, 100039, China. zxtian@genetics.ac.cn
- Publication Details
- Genome biology, Vol.18(1), pp.161-161
- Academic Unit
- Crop and Soil Sciences, Department of
- Publisher
- England
- Identifiers
- 99900547717201842
- Language
- English
- Resource Type
- Journal article