Journal article
Histones and their modifications during amphibian metamorphosis
Comparative biochemistry and physiology. B, Comparative biochemistry, Vol.39(3), pp.445-454
07/15/1971
Handle:
https://hdl.handle.net/2376/103855
PMID: 5315898
Abstract
1.1. Histones from all developmental stages of Rana catesbeiana in the liver and erythrocytes were found to be qualitatively similar.2.2. Gas chromatographic analysis revealed a decrease in hydrolyzable acetate on the histones as metamorphosis progressed to the adult or on thyroxine treatment.3.3. Isotope incorporation revealed a decrease in liver histone acetylation and no change in erythrocyte histone acetylation during metamorphosis.4.4. It is suggested that large scale acetylation of histones is not required for gene activation during metamorphosis.
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Details
- Title
- Histones and their modifications during amphibian metamorphosis
- Creators
- Michael D GriswoldGlenn J Miller
- Publication Details
- Comparative biochemistry and physiology. B, Comparative biochemistry, Vol.39(3), pp.445-454
- Academic Unit
- Molecular Biosciences, School of
- Publisher
- Elsevier Inc
- Identifiers
- 99900546849201842
- Language
- English
- Resource Type
- Journal article