Human liver carboxylesterase hCE-1 : Binding specificity for cocaine, heroin, and their metabolites and analogs

Journal article

Peer reviewed

M. R BRZEZINSKI, B. J SPINK, R. A DEAN, C. E BERKMAN, J. R CASHMAN and W. F BOSRON

Drug metabolism and disposition, Vol.25(9), pp.1089-1096

1997

Handle:

https://hdl.handle.net/2376/116490

PMID: 9311626

Abstract

Fundamental and applied biological sciences. Psychology

Drug addictions

Toxicology

Analytical, structural and metabolic biochemistry

Enzymes and enzyme inhibitors

Biological and medical sciences

Hydrolases

Medical sciences

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Title: Human liver carboxylesterase hCE-1 : Binding specificity for cocaine, heroin, and their metabolites and analogs
Creators: M. R BRZEZINSKI - Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, United States
B. J SPINK - Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, United States
R. A DEAN - Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, United States
C. E BERKMAN - Seattle Biomedical Research Institute, Seattle, WA, United States
J. R CASHMAN - Seattle Biomedical Research Institute, Seattle, WA, United States
W. F BOSRON - Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, United States
Publication Details: Drug metabolism and disposition, Vol.25(9), pp.1089-1096
Academic Unit: Chemistry, Department of
Publisher: American Society for Pharmacology and Experimental Therapeutics; Bethesda, MD
Identifiers: 99900547454301842
Language: English
Resource Type: Journal article