Journal article
Hypothalamic releasing hormones mediating the effects of interleukin‐1 on sleep
Journal of cellular biochemistry, Vol.53(4), pp.309-313
12/1993
Handle:
https://hdl.handle.net/2376/118260
PMID: 8300748
Abstract
There is a substantial literature describing the interactions between the endocrine and immune systems. Although such interactions are less well known within the brain, one major brain function altered during inflammation and infection and by several endocrine hormones is sleep. Pathological disturbances, be they inflammation, infectious disease, and/or sleep deprivation, result in altered hypothalamus‐pituitary function and cytokine metabolism. In respect to hormone secretion from the pituitary, cytokines are now recognized to play an important role in modulating the neuroendocrine system. Changes in sleep provide a useful illustration of the interactions between cytokines and the hypothalamus‐pituitary axis. Evidence linking interleukin‐1 (IL‐1) to growth hormone releasing hormone and to corticotropin releasing hormone in regard to their effects on sleep is reviewed.
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Details
- Title
- Hypothalamic releasing hormones mediating the effects of interleukin‐1 on sleep
- Creators
- Linda C PayneFerenc ObálJames M Krueger
- Publication Details
- Journal of cellular biochemistry, Vol.53(4), pp.309-313
- Academic Unit
- Integrative Physiology and Neuroscience, Department of
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; Hoboken
- Number of pages
- 5
- Identifiers
- 99900548155301842
- Language
- English
- Resource Type
- Journal article