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In situ molecular imaging of a hydrated biofilm in a microfluidic reactor by ToF-SIMS
Journal article

In situ molecular imaging of a hydrated biofilm in a microfluidic reactor by ToF-SIMS

Xin Hua, Xiao-Ying Yu, Zhaoying Wang, Li Yang, Bingwen Liu, Zihua Zhu, Abigail E Tucker, William B Chrisler, Eric A Hill, Theva Thevuthasan, …
Analyst (London), Vol.139(7), pp.1609-1613
2014
Handle:
https://hdl.handle.net/2376/110958
PMID: 24571001

Abstract

A novel microfluidic reactor for biofilm growth andin situcharacterization using time-of-flight secondary ion mass spectrometry (ToF-SIMS) was constructed to enable two-dimensional chemical imaging of hydrated biofilms. We demonstrate the detection of characteristic fatty acid fragments from microfluidic reactor-grown biofilms and illustrate advantages of hydrated-state ToF-SIMS imaging.

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