Journal article
In vitro antimicrobial and biological properties of laser assisted tricalcium phosphate coating on titanium for load bearing implant
Materials Science & Engineering C, Vol.29(6), pp.1965-1968
2009
Handle:
https://hdl.handle.net/2376/106856
PMID: 21461340
Abstract
Implant related infections are of great concern in modern surgery. In order to improve the implant performance and to reduce implant related infections, titanium (Ti) surface was modified to simultaneously improve cell-material interactions and antimicrobial activity. Ti surface was first coated with tricalcium phosphate (TCP) using Laser Engineered Net Shaping (LENS™) to improve biocompatibility. Silver (Ag) was then electrodeposited from different concentrations of silver nitrate (AgNO
3) solutions to improve the antimicrobial activity. The Ag-TCP coatings were tested for cytotoxicy with human osteoblast cells. The antimicrobial activities of the Ag-TCP coatings were evaluated using
Pseudomonas aeruginosa and
Staphylococcus aureus bacteria.
In vitro bacterial adhesion study indicated a significant reduction in bacterial colony on Ag-TCP coated surfaces when compared to TCP coated surface.
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Details
- Title
- In vitro antimicrobial and biological properties of laser assisted tricalcium phosphate coating on titanium for load bearing implant
- Creators
- Mangal RoyAmit BandyopadhyaySusmita Bose
- Publication Details
- Materials Science & Engineering C, Vol.29(6), pp.1965-1968
- Academic Unit
- Mechanical and Materials Engineering, School of
- Publisher
- Elsevier B.V
- Identifiers
- 99900546770101842
- Language
- English
- Resource Type
- Journal article