Journal article
In vivo endothelial cell infection by Anaplasma marginale
Veterinary pathology, Vol.44(1), pp.116-118
01/2007
Handle:
https://hdl.handle.net/2376/116643
PMID: 17197636
Abstract
Anaplasma marginale has recently been shown to infect endothelial cells in vitro, but it remains unknown as to whether endothelial infection also occurs in vivo. In this report, we demonstrate through dual fluorescence microscopy that A marginale, detected by the monoclonal antibody ANAF16C1, co-localizes with the endothelial cell marker, von Willebrand factor, in tissue sections from an experimentally inoculated calf. The results indicate that A marginale infection includes endothelial cells and has implications for both pathogenesis and immune mechanisms.
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Details
- Title
- In vivo endothelial cell infection by Anaplasma marginale
- Creators
- A D Carreño - Department of Pathobiology, Auburn University, AL 36849-5519, USAA R AllemanA F BarbetG H PalmerS M NohC M Johnson
- Publication Details
- Veterinary pathology, Vol.44(1), pp.116-118
- Academic Unit
- Paul G. Allen School for Global Animal Health
- Publisher
- United States
- Identifiers
- 99900548267701842
- Language
- English
- Resource Type
- Journal article