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Inexpensive Purification of P450 Reductase and Other Proteins Using 2′,5′-Adenosine Diphosphate Agarose Affinity Columns
Journal article   Peer reviewed

Inexpensive Purification of P450 Reductase and Other Proteins Using 2′,5′-Adenosine Diphosphate Agarose Affinity Columns

Dan Rock, Denise Rock and Jeffrey P Jones
Protein expression and purification, Vol.22(1), pp.82-83
06/2001
Handle:
https://hdl.handle.net/2376/113085
PMID: 11388803

Abstract

Two reductases, P450 oxidoreductase and P450Bm-3 reductase, were purified on a 2′,5′-adenosine diphosphate solid support. Although the efficiency of these columns is well established, the cost of the resin and the eluting material 2′-adenosine can be prohibitive. Herein we show that the less costly 2′,3′-adenosine monophosphate is an excellent eluting material.

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