Journal article
Influence of ZnO doping in calcium phosphate ceramics
Materials Science & Engineering C, Vol.27(1), pp.14-17
2007
Handle:
https://hdl.handle.net/2376/104267
Abstract
Tricalcium phosphate (TCP) and hydroxyapatite (HAp) samples with varying concentrations of zinc oxide (ZnO) ranging from 0.5 to 3.5 wt.% were fabricated by uniaxial pressing followed by sintering at 1250 and 1300 °C to understand the role of ZnO in densification, microhardness and cell-materials interaction. Variation in the amount of ZnO present in TCP and HAp showed differences in sintering behavior. At a sintering temperature of 1250 °C both TCP and HAp experienced an increase in densification with increasing ZnO content. Up to 2.5 wt.% of ZnO addition increased microhardness for TCP, and then decreased it. Samples sintered at 1250 °C proved to be harder than those sintered at 1300 °C. Analysis of microstructure using SEM revealed that grain size changed due to ZnO doping in TCP, but had limited influence on HAp. Preliminary in vitro cell–materials interaction study showed that osteoblast cells were adhered well after 5 days on surfaces containing up to 1.5 wt.% ZnO. Higher ZnO doping had deleterious effects on cell attachments and growth. For 3.5 wt.% ZnO doped samples, cell death was observed.
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Details
- Title
- Influence of ZnO doping in calcium phosphate ceramics
- Creators
- Amit Bandyopadhyay - School of Mechanical and Materials Engineering, Washington State University, USAElizabeth A Withey - NSF-REU Student at WSU from Purdue University, USAJessica Moore - School of Biological Sciences, Washington State University, Pullman, WA 99164, USASusmita Bose
- Publication Details
- Materials Science & Engineering C, Vol.27(1), pp.14-17
- Academic Unit
- Mechanical and Materials Engineering, School of
- Publisher
- Elsevier B.V
- Identifiers
- 99900546994701842
- Language
- English
- Resource Type
- Journal article