Journal article
Inheritance patterns of the transcriptome in hybrid chickens and their parents revealed by expression analysis
Scientific reports, Vol.9(1), pp.5750-5750
04/08/2019
Handle:
https://hdl.handle.net/2376/110234
PMCID: PMC6453914
PMID: 30962479
Abstract
Although many phenotypic traits of chickens have been well documented, the genetic patterns of gene expression levels in chickens remain to be determined. In the present study, we crossed two chicken breeds, White Leghorn (WL) and Cornish (Cor), which have been selected for egg and meat production, respectively, for a few hundred years. We evaluated transcriptome abundance in the brain, muscle, and liver from the day-old progenies of pure-bred WL and Cor, and the hybrids of these two breeds, by RNA-Seq in order to determine the inheritance patterns of gene expression. Comparison among expression levels in the different groups revealed that most of the genes showed conserved expression patterns in all three examined tissues and that brain had the highest number of conserved genes, which indicates that conserved genes are predominantly important compared to others. On the basis of allelic expression analysis, in addition to the conserved genes, we identified the extensive presence of additive, dominant (Cor dominant and WL dominant), over-dominant, and under-dominant genes in all three tissues in hybrids. Our study is the first to provide an overview of inheritance patterns of the transcriptome in layers and broilers, and we also provide insights into the genetics of chickens at the gene expression level.
Metrics
8 Record Views
Details
- Title
- Inheritance patterns of the transcriptome in hybrid chickens and their parents revealed by expression analysis
- Creators
- Hongchang Gu - Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaXin Qi - Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaYaxiong Jia - Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, ChinaZebin Zhang - Division of Population Genetics, Department of Zoology, Stockholm University, Stockholm, SwedenChangsheng Nie - Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaXinghua Li - Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaJunying Li - Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, ChinaZhihua Jiang - Department of Animal Sciences, Center for Reproductive Biology, Veterinary and Biomedical Research Building, Washington State University, Pullman, United StatesQiong Wang - Key Laboratory of Sustainable Development of Marine Fisheries, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, China. wangqiong@ysfri.ac.cnLujiang Qu - Department of Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, China. quluj@163.com
- Publication Details
- Scientific reports, Vol.9(1), pp.5750-5750
- Academic Unit
- Animal Sciences, Department of; Crop and Soil Sciences, Department of
- Publisher
- England
- Identifiers
- 99900547015901842
- Language
- English
- Resource Type
- Journal article