Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4- dimethyl-benziso-(2H)- selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase

Journal article

Open access

David J GREENBLATT, Diane E PETERS, Lauren E OLESON, Jerold S HARMATZ, Malcolm W MACNAB, Noah BERKOWITZ, Miguel A ZINNY and Michael H COURT

British journal of clinical pharmacology, Vol.68(6), pp.920-927

2009

Handle:

https://hdl.handle.net/2376/106351

PMCID: PMC2810804

PMID: 20002087

Files and links (1)

url

https://doi.org/10.1111/j.1365-2125.2009.03545.xView

Published (Version of record) Open

Biological and medical sciences

Pharmacology. Drug treatments

Medical sciences

8 Record Views

Title: Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4- dimethyl-benziso-(2H)- selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase
Creators: David J GREENBLATT - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts Medical Center, United States
Diane E PETERS - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts Medical Center, United States
Lauren E OLESON - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts Medical Center, United States
Jerold S HARMATZ - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts Medical Center, United States
Malcolm W MACNAB - Synvista Therapeutics, Inc, Montvale, NJ, United States
Noah BERKOWITZ - Synvista Therapeutics, Inc, Montvale, NJ, United States
Miguel A ZINNY - ProMedica Clinical Research Center, Boston MA, United States
Michael H COURT - Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts Medical Center, United States
Publication Details: British journal of clinical pharmacology, Vol.68(6), pp.920-927
Academic Unit: Veterinary Clinical Sciences, Department of
Publisher: Blackwell; Oxford
Identifiers: 99900546607801842
Language: English
Resource Type: Journal article