Journal article
Inorganic hydrogen polysulfides: chemistry, chemical biology and detection
British journal of pharmacology, Vol.176(4), pp.616-627
02/2019
Handle:
https://hdl.handle.net/2376/116823
PMCID: PMC6346069
PMID: 29669174
Abstract
Recent studies suggest that inorganic hydrogen polysulfides (H
S
, n ≥ 2) play important regulatory roles in redox biology. Modulation of their cellular levels could have potential therapeutic value. This review article focuses on our current understanding of the biosynthesis, biofunctions, fundamental physical/chemical properties, detection methods and delivery techniques of H
S
. LINKED ARTICLES: This article is part of a themed section on Chemical Biology of Reactive Sulfur Species. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.4/issuetoc.
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Details
- Title
- Inorganic hydrogen polysulfides: chemistry, chemical biology and detection
- Creators
- Heng Liu - Department of Chemistry, Washington State University, Pullman, WA, USAMiles N Radford - Department of Chemistry, Washington State University, Pullman, WA, USAChun-Tao Yang - Key Laboratory of Molecular Clinical Pharmacology, School of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong, ChinaWei Chen - Department of Chemistry, Washington State University, Pullman, WA, USAMing Xian - Key Laboratory of Molecular Clinical Pharmacology, School of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong, China
- Publication Details
- British journal of pharmacology, Vol.176(4), pp.616-627
- Academic Unit
- Chemistry, Department of
- Publisher
- England
- Grant note
- R01 GM125968 / NIGMS NIH HHS
- Identifiers
- 99900547931201842
- Language
- English
- Resource Type
- Journal article