Journal article
Kinesin-II, the heteromeric kinesin
Cellular and molecular life sciences : CMLS, Vol.56(3-4), pp.217-226
10/15/1999
Handle:
https://hdl.handle.net/2376/112506
PMID: 11212349
Abstract
The kinesins constitute a large family of motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. One class of these molecular motors, kinesin-II, is unique in that these proteins are typically found as heterotrimeric complexes containing two different, though related, kinesin-like motor subunits, and a single nonmotor subunit. The heteromeric nature of these kinesins appears to have resulted in a class of combinatorial kinesins which can 'mix and match' different motor subunits. Another novel feature of these motors is that the activities of several kinesin-II representatives are essential in the assembly of motile and nonmotile cilia, a role not attributed to any other kinesin. This review presents a brief overview of the structure and biological functions of kinesin-II, the heteromeric kinesin.
Metrics
9 Record Views
Details
- Title
- Kinesin-II, the heteromeric kinesin
- Creators
- D G Cole - Department of Microbiology, Molecular Biology and Biochemistry, University of Idaho, Moscow 83844-3052, USA. dcole@uidaho.edu
- Publication Details
- Cellular and molecular life sciences : CMLS, Vol.56(3-4), pp.217-226
- Academic Unit
- Center for Reproductive Biology
- Publisher
- Switzerland
- Grant note
- GM14642 / NIGMS NIH HHS
- Identifiers
- 99900547736401842
- Language
- English
- Resource Type
- Journal article