Kinetic isotope effects implicate the iron-oxene as the sole oxidant in P450-catalyzed N-dealkylation

Journal article

Tamara S DOWERS, Dan A ROCK, Denise A ROCK and Jeffrey P JONES

Journal of the American Chemical Society, Vol.126(29), pp.8868-8869

2004

Handle:

https://hdl.handle.net/2376/112752

PMID: 15264797

Abstract

Fundamental and applied biological sciences. Psychology

Physical chemistry in biology

Organic chemistry

Chemistry

Kinetics and mechanisms

Reactivity and mechanisms

Exact sciences and technology

Molecular biophysics

Biological and medical sciences

Mechanisms. Catalysis. Electron transfer. Models

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Title: Kinetic isotope effects implicate the iron-oxene as the sole oxidant in P450-catalyzed N-dealkylation
Creators: Tamara S DOWERS - Department of Chemistry, P.O. Box 644630, Washington State University, Pullman, Washington 99164-4630, United States
Dan A ROCK - Department of Chemistry, P.O. Box 644630, Washington State University, Pullman, Washington 99164-4630, United States
Denise A ROCK - Department of Chemistry, P.O. Box 644630, Washington State University, Pullman, Washington 99164-4630, United States
Jeffrey P JONES - Department of Chemistry, P.O. Box 644630, Washington State University, Pullman, Washington 99164-4630, United States
Publication Details: Journal of the American Chemical Society, Vol.126(29), pp.8868-8869
Academic Unit: Chemistry, Department of
Publisher: American Chemical Society; Washington, DC
Identifiers: 99900547881901842
Language: English
Resource Type: Journal article