Journal article
Large-pore mesoporous SBA-15 silica particles with submicrometer size as stationary phases for high-speed CEC separation
Electrophoresis, Vol.27(4), pp.742-748
02/2006
Handle:
https://hdl.handle.net/2376/112460
PMID: 16421943
Abstract
A new mesoporous sphere-like SBA-15 silica was synthesized and evaluated in terms of its suitability as stationary phases for CEC. The unique and attractive properties of the silica particle are its submicrometer particle size of 400 nm and highly ordered cylindrical mesopores with uniform pore size of 12 nm running along the same direction. The bare silica particles with submicrometer size have been successfully employed for the normal-phase electrochromatographic separation of polar compounds with high efficiency (e.g., 210,000 for thiourea), which is matched well with its submicrometer particle size. The Van Deemeter plot showed the hindrance to mass transfer because of the existence of pore structure. The lowest plate height of 2.0 microm was obtained at the linear velocity of 1.1 mm/s. On the other hand, because of the relatively high linear velocity (e.g., 4.0 mm/s) can be generated, high-speed separation of neutral compounds, anilines, and basic pharmaceuticals in CEC with C18-modified SBA-15 silica as stationary phases was achieved within 36, 60, and 34 s, respectively.
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Details
- Title
- Large-pore mesoporous SBA-15 silica particles with submicrometer size as stationary phases for high-speed CEC separation
- Creators
- Ruijun Tian - National Chromatographic R&A Center, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian, PR ChinaJunming SunHe ZhangMingliang YeChuanhui XieJin DongJiwei HuDing MaXinhe BaoHanfa Zou
- Publication Details
- Electrophoresis, Vol.27(4), pp.742-748
- Academic Unit
- School of Chemical Engineering and Bioengineering
- Publisher
- Germany
- Identifiers
- 99900547993601842
- Language
- English
- Resource Type
- Journal article