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CC BY-NC V4.0, Open Access
Journal article
Long-term nighttime aircraft noise exposure and risk of hypertension in a prospective cohort of female nurses
International journal of hygiene and environmental health, Vol.263, p.114457
01/2025
PMID: 39270405
Appears in Aviation Sustainability Center (ASCENT)
Abstract
There is growing interest in cardiometabolic outcomes associated with nighttime noise, given that noise can disturb sleep and sleep disturbance can increase cardiometabolic risk such as hypertension. However, there is little empirical research evaluating the association between nighttime aircraft noise and hypertension risk. In this study, we expand on previous work to evaluate associations between nighttime aircraft noise exposure and self-reported hypertension incidence in the Nurses' Health Studies (NHS/NHSII), two US-wide cohorts of female nurses. Annual nighttime average aircraft sound levels (L
) surrounding 90 airports for 1995-2015 (in 5-year intervals) were modeled using the Aviation Environmental Design Tool and assigned to participants' geocoded addresses over time. Hypertension risk was estimated for each cohort using time-varying Cox proportional-hazards models for L
dichotomized at 45 dB (dB), adjusting for individual-level hypertension risk factors, area-level socioeconomic status, region, and air pollution. Random effects meta-analysis was used to combine cohort results. Among 63,229 NHS and 98,880 NHSII participants free of hypertension at study baseline (1994/1995), we observed 33,190 and 28,255 new hypertension cases by 2014/2013, respectively. Although ∼1% of participants were exposed to L
≥45 dB, we observed an adjusted hazard ratio (HR) of 1.10 (95% CI: 0.96, 1.27) in NHS and adjusted HR of 1.12 (95% CI: 0.98, 1.28) in NHSII, comparing exposure to L
≥45 versus <45 dB(A). In meta-analysis, we observed an adjusted HR of 1.11 (95% CI: 1.01, 1.23). These results were attenuated with adjustment for additional variables such as body mass index. Our findings support a modest positive association between nighttime aircraft noise and hypertension risk across NHS/NHSII, which may reinforce the concept that sleep disturbance contributes to noise-related disease burden.
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Details
- Title
- Long-term nighttime aircraft noise exposure and risk of hypertension in a prospective cohort of female nurses
- Creators
- Junenette L Peters - Boston UniversityStephanie T Grady - Boston UniversityFrancine Laden - Brigham and Women's HospitalElizabeth Nelson - Boston UniversityMatthew Bozigar - Boston UniversityJaime E Hart - Brigham and Women's HospitalJoAnn E Manson - Harvard UniversityTianyi Huang - Brigham and Women's HospitalSusan Redline - Brigham and Women's HospitalJoel D Kaufman - University of WashingtonJohn P Forman - Brigham and Women's HospitalKathryn M Rexrode - Brigham and Women's HospitalJonathan I Levy - Boston University
- Publication Details
- International journal of hygiene and environmental health, Vol.263, p.114457
- Academic Unit
- Aviation Sustainability Center (ASCENT); Noise
- Grants
- 13-C-AJFE-BU-016, Federal Aviation Administration (United States, Washington) - FAA13-C-AJFE-BU-002, Federal Aviation Administration (United States, Washington) - FAA13-C-AJFE-BU-004, Federal Aviation Administration (United States, Washington) - FAA13-C-AJFE-BU-006, Federal Aviation Administration (United States, Washington) - FAA13-C-AJFE-BU-012, Federal Aviation Administration (United States, Washington) - FAA13-C-AJFE-BU-032, Federal Aviation Administration (United States, Washington) - FAA
- Grant note
- U01 HL145386 / NHLBI NIH HHS R01 ES025791 / NIEHS NIH HHS R01 HL150119 / NHLBI NIH HHS R01 ES027696 / NIEHS NIH HHS R01 HL034594 / NHLBI NIH HHS T32 ES014562 / NIEHS NIH HHS U01 CA176726 / NCI NIH HHS R01 HL035464 / NHLBI NIH HHS P30 ES000002 / NIEHS NIH HHS P30 ES007033 / NIEHS NIH HHS
- Identifiers
- 99901177541301842
- Language
- English
- Resource Type
- Journal article