Journal article
Low numbers of intestinal Shiga toxin-producing E. coli correlate with a poor prognosis in sheep infected with bovine leukemia virus
Journal of veterinary science (Suwŏn-si, Korea), Vol.9(4), pp.375-379
12/2008
Handle:
https://hdl.handle.net/2376/110235
PMCID: PMC2811778
PMID: 19043312
Abstract
Healthy ruminants carry intestinal Shiga toxin (Stx)-producing
Escherichia coli
(STEC). Stx has antiviral activities
in vitro
and STEC numbers correlate with reduced early viremia in sheep experimentally infected with bovine leukemia virus (BLV). This study assessed the impact of intestinal STEC on BLV-induced disease for one year post-BLV-challenge. High STEC scores (CFU/g feces × frequency of STEC-positive samples) correlated with good health, whereas poor weight gain, distress, and tumor development occurred only among animals with low STEC scores. STEC carriage was associated with increased percentages of B cells in peripheral blood.
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Details
- Title
- Low numbers of intestinal Shiga toxin-producing E. coli correlate with a poor prognosis in sheep infected with bovine leukemia virus
- Creators
- Witold A Ferens - Department of Microbiology, Molecular Biology and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USAJulius Haruna - Department of Veterinary Microbiology and Pathology, Washington Animal Disease Diagnostic Laboratory, College of Veterinary Medicine, Washington State University, Pullman WA, 99164, USARowland Cobbold - Field Disease Investigation Unit, Washington State University, Pullman WA, 99164-6610, USACarolyn J Hovde - Department of Microbiology, Molecular Biology and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA
- Publication Details
- Journal of veterinary science (Suwŏn-si, Korea), Vol.9(4), pp.375-379
- Publisher
- The Korean Society of Veterinary Science
- Identifiers
- 99900547262901842
- Language
- English
- Resource Type
- Journal article