Mechanisms for reaching the differentiated state: Insights from neural crest-derived melanocytes

Cynthia D Cooper; David W Raible

doi:10.1016/j.semcdb.2008.09.008

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Mechanisms for reaching the differentiated state: Insights from neural crest-derived melanocytes

Journal article

Open access

Peer reviewed

Mechanisms for reaching the differentiated state: Insights from neural crest-derived melanocytes

Cynthia D Cooper and David W Raible

Seminars in cell & developmental biology, Vol.20(1), pp.105-110

2009

DOI: https://doi.org/10.1016/j.semcdb.2008.09.008

Handle:

https://hdl.handle.net/2376/110379

PMCID: PMC2730768

PMID: 18935965

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Abstract

Melanocytes

Specification

Differentiation

Neural crest

Black pigment cells, or melanocytes, are the major contributing cells to pigmentation in vertebrate organisms. Although the function of these cells is distinct depending on the organism, the events involved in their development are remarkably similar. Here, we review the mechanisms involved in the early development of melanocytes from neural crest, many of which are conserved in organisms as diverse as zebrafish, birds and humans. We also discuss recent studies that provide further insight into how melanocyte differentiation is achieved and maintained.

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Details

Title: Mechanisms for reaching the differentiated state: Insights from neural crest-derived melanocytes
Creators: Cynthia D Cooper
David W Raible
Publication Details: Seminars in cell & developmental biology, Vol.20(1), pp.105-110
Academic Unit: Molecular Biosciences, School of
Publisher: Elsevier Ltd
Identifiers: 99900547030601842
Language: English
Resource Type: Journal article