Journal article
Microinjection of morphine into the rostral ventromedial medulla produces greater antinociception in male compared to female rats
Brain research, Vol.796(1), pp.315-318
1998
Handle:
https://hdl.handle.net/2376/106004
PMID: 9689486
Abstract
The antinociceptive and locomotor effects of microinjecting morphine into the rostral ventromedial medulla (RVM) of male and female rats was assessed. Male rats showed greater antinociception than female rats at all doses and times following morphine administration. Male, but not female rats, also showed a dose dependent decrease in locomotion. These data demonstrate that sex differences in antinociception are mediated at least in part by the RVM.
Metrics
12 Record Views
Details
- Title
- Microinjection of morphine into the rostral ventromedial medulla produces greater antinociception in male compared to female rats
- Creators
- Jill S Boyer - Department of Psychology, Washington State University, 14204 NE Salmon Creek Ave., Vancouver, WA 98686, USAMichael M Morgan - Department of Psychology, Washington State University, 14204 NE Salmon Creek Ave., Vancouver, WA 98686, USARebecca M Craft - Department of Psychology, Washington State University, Pullman, WA 99164, USA
- Publication Details
- Brain research, Vol.796(1), pp.315-318
- Academic Unit
- Psychology, Department of
- Publisher
- Elsevier B.V
- Identifiers
- 99900547067901842
- Language
- English
- Resource Type
- Journal article