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Morphological Transformation between Nanofibers and Vesicles in a Controllable Bipyridine–Tripeptide Self‐Assembly
Journal article   Peer reviewed

Morphological Transformation between Nanofibers and Vesicles in a Controllable Bipyridine–Tripeptide Self‐Assembly

Damei Ke, Chuanlang Zhan, Alexander D. Q Li and Jiannian Yao
Angewandte Chemie (International ed.), Vol.50(16), pp.3715-3719
04/11/2011
Handle:
https://hdl.handle.net/2376/113152
PMID: 21472901

Abstract

peptides morphological transformation nanofibers self‐assembly vesicles
Tuning structures: Stimulus‐responsive peptide self‐assembly requires a balance of conformational change and structural continuity of stable β sheets. In an amphiphilic bipyridine–tripeptide model, temperature, and ultrasound switch a reversible morphological transformation between vesicles and nanofibers (see picture) through the synergistic effects of terminal β‐sheet‐forming peptides, flexible linkers, and rotatable bipyridine groups.

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