Journal article
Multiresistant Salmonella Typhimurium DT104 infections of humans and domestic animals in the Pacific Northwest of the United States
Epidemiology and infection, Vol.124(2), pp.193-200
04/2000
Handle:
https://hdl.handle.net/2376/113391
PMCID: PMC2810900
PMID: 10813142
Abstract
Salmonella Typhimurium definitive type 104 with chromosomally encoded resistance to five or
more antimicrobial drugs (R-type ACSSuT+) has been reported increasingly frequently as the
cause of human and animal salmonellosis since 1990. Among animal isolates from the
northwestern United States (NWUS), R-type ACSSuT+ Typhimurium isolates increased
through the early 1990s to comprise 73% of Typhimurium isolates by 1995, but subsequently
decreased to comprise only 30% of isolates during 1998. NWUS S. Typhimurium R-type
ACSSuT+ were consistently (99%) phage typed as DT104 or the closely related DTu302. S.
Typhimurium isolates from cattle with primary salmonellosis, randomly selected from a
national repository, from NWUS were more likely to exhibit R-type ACSSuT+ (19/24, 79%)
compared to isolates from other quadrants (17/71, 24%; P < 0.01). Human patients infected
with R-type ACSSuT+ resided in postal zip code polygons of above average cattle farm
density (P < 0.05), while patients infected with other R-types showed no similar tendency.
Furthermore, humans infected with R-type ACSSuT+ Typhimurium were more likely to
report direct contact with livestock (P < 0.01) than humans infected with other R-types.
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Details
- Title
- Multiresistant Salmonella Typhimurium DT104 infections of humans and domestic animals in the Pacific Northwest of the United States
- Creators
- T. E BESSER - Department of Veterinary Microbiology and Pathology, P.O. Box 647040, Washington State University, Pullman WA 99164-7040, USAM GOLDOFT - Communicable Disease Epidemiology Section, Washington State Department of Health, 1610 NE 150th St, Shoreline WA 98155, USAL. C PRITCHETT - Field Disease Investigation Unit, Washington State University, Pullman WA 99164-7060, USAR KHAKHRIA - National Laboratory for Enteric Pathogens, Health Canada, HPB/IPS Bldg #7 AL, Tunney's Pasture, Ottawa Ontario Canada K1A 0L2D. D HANCOCK - Field Disease Investigation Unit, Washington State University, Pullman WA 99164-7060, USAD. H RICE - Field Disease Investigation Unit, Washington State University, Pullman WA 99164-7060, USAJ. M GAY - Field Disease Investigation Unit, Washington State University, Pullman WA 99164-7060, USAW JOHNSON - National Laboratory for Enteric Pathogens, Health Canada, HPB/IPS Bldg #7 AL, Tunney's Pasture, Ottawa Ontario Canada K1A 0L2C. C GAY - Field Disease Investigation Unit, Washington State University, Pullman WA 99164-7060, USA
- Publication Details
- Epidemiology and infection, Vol.124(2), pp.193-200
- Academic Unit
- Veterinary Clinical Sciences, Department of; Veterinary Microbiology and Pathology, Department of
- Publisher
- Cambridge University Press
- Number of pages
- 8
- Identifiers
- 99900547945701842
- Language
- English
- Resource Type
- Journal article