Journal article
Nanomaterial labels in electrochemical immunosensors and immunoassays
Talanta (Oxford), Vol.74(3), pp.308-317
2007
Handle:
https://hdl.handle.net/2376/104627
PMCID: PMC2819410
PMID: 18371644
Abstract
This article reviews recent advances in nanomaterial labels in electrochemical immunosensors and immunoassays. Various nanomaterial labels are discussed, including colloidal gold/silver, semiconductor nanoparticles, and markers loaded nanocarriers (carbon nanotubes, apoferritin, silica nanoparticles, and liposome beads). The enormous signal enhancement associated with the use of nanomaterial labels and with the formation of nanomaterial–antibody–antigen assemblies provides the basis for ultrasensitive electrochemical detection of disease-related protein biomarkers, biothreat agents, or infectious agents. In general, all endeavors cited here are geared to achieve one or more of the following goals: signal amplification by several orders of magnitude, lower detection limits, and detecting multiple targets.
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Details
- Title
- Nanomaterial labels in electrochemical immunosensors and immunoassays
- Creators
- Guodong Liu - Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, ND 58105-5516, United StatesYuehe Lin - Pacific Northwest National Laboratory, Richland, WA 99352, United States
- Publication Details
- Talanta (Oxford), Vol.74(3), pp.308-317
- Academic Unit
- Mechanical and Materials Engineering, School of
- Publisher
- Elsevier B.V
- Identifiers
- 99900546716501842
- Language
- English
- Resource Type
- Journal article