Journal article
Neuropsychological functioning of youths with sickle cell disease: comparison with non-chronically ill peers
Journal of pediatric psychology, Vol.26(2), pp.69-78
03/2001
Handle:
https://hdl.handle.net/2376/109441
PMID: 11181883
Abstract
To compare the neuropsychological functioning of children with sickle cell disease (SCD) with no evidence of overt clinical stroke to that of classmates without a chronic illness matched on gender, race, and age. We examined both overall level of performance and patterns of performance utilizing empirically derived construct scores of key domains of neurocognitive functioning.
An abbreviated neuropsychological battery of tests was given to 31 children with SCD and 31 case controls. Empirically derived construct scores were developed for primary analyses.
Children with SCD had significantly lower scores on three level-of-performance construct scores: total, verbal, and attention/memory. Mean scores for children with SCD were lower than those for case controls on every level-of-performance construct score and every standardized test score. However, pattern-of-performance construct scores were not significantly different.
Children with SCD without overt stroke demonstrate significant deficits in neurocognitive functioning compared to classroom case controls. These findings highlight the impact of SCD on general neurocognitive functioning and suggest that routine screening of cognitive functioning should be a requisite element of comprehensive care for children with SCD. Within the context of documented physical limitations, we conclude that children with SCD are at very high risk for impaired psychosocial outcomes.
Metrics
9 Record Views
Details
- Title
- Neuropsychological functioning of youths with sickle cell disease: comparison with non-chronically ill peers
- Creators
- R B Noll - Division of Hematology/Oncology, Children's Hospital Medical Center, University of Cincinnati, USA. nollr0@chmcc.orgL StithM A GartsteinM D RisR GrueneichK VannattaK Kalinyak
- Publication Details
- Journal of pediatric psychology, Vol.26(2), pp.69-78
- Academic Unit
- Psychology, Department of
- Publisher
- United States
- Identifiers
- 99900547797401842
- Language
- English
- Resource Type
- Journal article