Journal article
Neutral Evolution of Multiple Quantitative Characters: A Genealogical Approach
Genetics (Austin), Vol.176(1), pp.455-466
05/2007
Handle:
https://hdl.handle.net/2376/116840
PMCID: PMC1893077
PMID: 17339224
Abstract
The
G
matrix measures the components of phenotypic variation that are genetically heritable. The structure of
G
, that is, its principal components and their associated variances, determines, in part, the direction and speed of multivariate trait evolution. In this article we present a framework and results that give the structure of
G
under the assumption of neutrality. We suggest that a neutral expectation of the structure of
G
is important because it gives a null expectation for the structure of
G
from which the unique consequences of selection can be determined. We demonstrate how the processes of mutation, recombination, and drift shape the structure of
G
. Furthermore, we demonstrate how shared common ancestry between segregating alleles shapes the structure of
G
. Our results show that shared common ancestry, which manifests itself in the form of a gene genealogy, causes the structure of
G
to be nonuniform in that the variances associated with the principal components of
G
decline at an approximately exponential rate. Furthermore we show that the extent of the nonuniformity in the structure of
G
is enhanced with declines in mutation rates, recombination rates, and numbers of loci and is dependent on the pattern and modality of mutation.
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Details
- Title
- Neutral Evolution of Multiple Quantitative Characters: A Genealogical Approach
- Creators
- Cortland K Griswold - School of Biological SciencesBenjamin Logsdon - School of Biological SciencesRichard Gomulkiewicz - School of Biological Sciences
- Publication Details
- Genetics (Austin), Vol.176(1), pp.455-466
- Academic Unit
- Biological Sciences, School of
- Publisher
- Copyright © 2007 by the Genetics Society of America
- Identifiers
- 99900548253301842
- Language
- English
- Resource Type
- Journal article