Journal article
New zinc(II)-based catalyst for asymmetric azomethine ylide cycloaddition reactions
Organic letters, Vol.8(21), pp.4687-4690
10/12/2006
Handle:
https://hdl.handle.net/2376/106676
PMID: 17020278
Abstract
[reaction: see text] A new chiral aziridino alcohol ligand for zinc(II)-catalyzed azomethine ylide cycloadditions is described. In the presence of this catalyst, N-arylidene glycine methyl esters react with a variety of dipolarophiles to give substituted pyrrolidines in very good to excellent chemical yields and up to 95% ee. The absolute sense of asymmetric induction appears to be dipolarophile-dependent.
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Details
- Title
- New zinc(II)-based catalyst for asymmetric azomethine ylide cycloaddition reactions
- Creators
- Ozdemir Dogan - Department of Chemistry, Middle East Technical University, 06531 Ankara, Turkey. dogano@metu.edu.trHasan KoyuncuPhilip GarnerAdnan BulutWiley J YoungsMatthew Panzner
- Publication Details
- Organic letters, Vol.8(21), pp.4687-4690
- Academic Unit
- Chemistry, Department of
- Publisher
- United States
- Identifiers
- 99900546894301842
- Language
- English
- Resource Type
- Journal article