Journal article
Ovarian aging in developmental and evolutionary contexts
Annals of the New York Academy of Sciences, Vol.1204(1), pp.82-94
08/2010
Handle:
https://hdl.handle.net/2376/109065
PMID: 20738278
Abstract
Evolutionary theory predicts that aging-related fertility declines result from tradeoffs between reproduction and somatic maintenance. Developmental programs for oogenesis also contribute to variation in aging-related reproductive declines among female vertebrates. Documented reproductive aging patterns in female vertebrates, including humans, are consistent with canonical aging patterns determined developmentally and require no special adaptive explanation. Here we discuss patterns of aging-related ovarian decline in diverse female vertebrates, and place human ovarian aging in comparative context. Depletion of finite oocyte stores accompanied by fertility loss occurs in a variety of nonhuman mammals and vertebrates, including short-lived rodents, birds, and some fishes; moreover, postreproductive lifespans of considerable length clearly are not limited to long-lived, social species with well-developed kin networks. We argue for a more rigorous comparative approach for understanding the evolutionary and developmental bases of ovarian aging in vertebrates with a wider range of aging patterns and social structures.
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Details
- Title
- Ovarian aging in developmental and evolutionary contexts
- Creators
- Caleb E Finch - Ethel Percy Andrus Gerontology Center, Department of Biological Sciences, University of Southern California, Los Angeles, California, USADonna J Holmes
- Publication Details
- Annals of the New York Academy of Sciences, Vol.1204(1), pp.82-94
- Academic Unit
- Center for Reproductive Biology
- Publisher
- United States
- Grant note
- AG14571 / NIA NIH HHS AG026752 / NIA NIH HHS
- Identifiers
- 99900547209801842
- Language
- English
- Resource Type
- Journal article