Journal article
Oxidase-Like Fe-N-C Single-Atom Nanozymes for the Detection of Acetylcholinesterase Activity
Small (Weinheim an der Bergstrasse, Germany), Vol.15(43), pp.1-7
10/01/2019
PMID: 31482681
Abstract
Single-atom catalysts (SACs) have attracted extensive attention in the catalysis field because of their remarkable catalytic activity, gratifying stability, excellent selectivity, and 100% atom utilization. With atomically dispersed metal active sites, Fe-N-C SACs can mimic oxidase by activating O-2 into reactive oxygen species, O-2(-)center dot radicals. Taking advantages of this property, single-atom nanozymes (SAzymes) can become a great impetus to develop novel biosensors. Herein, the performance of Fe-N-C SACs as oxidase-like nanozymes is explored. Besides, the Fe-N-C SAzymes are applied in biosensor areas to evaluate the activity of acetylcholinesterase based on the inhibition toward nanozyme activity by thiols. Moreover, this SAzymes-based biosensor is further used for monitoring the amounts of organophosphorus compounds.
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Details
- Title
- Oxidase-Like Fe-N-C Single-Atom Nanozymes for the Detection of Acetylcholinesterase Activity
- Creators
- Yu Wu - Central China Normal UniversityLei Jiao - Central China Normal UniversityXin Luo - Central China Normal UniversityWeiqing Xu - Central China Normal UniversityXiaoqian Wei - Central China Normal UniversityHengjia Wang - Central China Normal UniversityHongye Yan - Central China Normal UniversityWenling Gu - Central China Normal UniversityBo Z. Xu - University of California, BerkeleyDan Du - Washington State UniversityYuehe Lin - Washington State UniversityChengzhou Zhu - Central China Normal University
- Publication Details
- Small (Weinheim an der Bergstrasse, Germany), Vol.15(43), pp.1-7
- Academic Unit
- School of Mechanical and Materials Engineering
- Publisher
- Wiley
- Number of pages
- 7
- Identifiers
- 99901227640401842
- Language
- English
- Resource Type
- Journal article