Journal article
PEARLS depression treatment for individuals with epilepsy: A randomized controlled trial
Epilepsy & behavior, Vol.19(3), pp.225-231
2010
Handle:
https://hdl.handle.net/2376/113843
PMID: 20609631
Abstract
Depression is associated with higher rates of suicide and lower levels of functioning and quality of life in individuals with epilepsy. The objective of this randomized controlled trial was to determine the effectiveness of PEARLS, a home-based program for managing depression in adult individuals with epilepsy and clinically significant acute and chronic depression.
Delivered by masters-level counselors, PEARLS is a collaborative care intervention consisting of problem solving treatment, behavioral activation, and psychiatric consultation. Patients were randomly assigned to the PEARLS intervention (
N
=
40) or usual care (
N
=
40), and assessed at baseline, 6
months, and 12
months.
Compared with patients who received usual care, patients assigned to the PEARLS intervention achieved lower depression severity (
P
<
0.005) (Hopkins Symptoms Checklist-20) and lower suicidal ideation (
P
=
0.025) over 12
months.
The PEARLS program, a community-integrated, home-based treatment for depression, effectively reduces depressive symptoms in adults with epilepsy and comorbid depression.
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Details
- Title
- PEARLS depression treatment for individuals with epilepsy: A randomized controlled trial
- Creators
- Paul Ciechanowski - Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USANaomi Chaytor - Department of Neurology, University of Washington, Seattle, WA, USAJohn Miller - Department of Neurology, University of Washington, Seattle, WA, USARobert Fraser - Department of Neurology, University of Washington, Seattle, WA, USAJoan Russo - Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USAJurgen Unutzer - Department of Neurology, University of Washington, Seattle, WA, USAFrank Gilliam - Department of Neurology, Geisinger Health System, Danville, PA, USA
- Publication Details
- Epilepsy & behavior, Vol.19(3), pp.225-231
- Academic Unit
- Medical Education and Clinical Science, Department of
- Publisher
- Elsevier Inc
- Identifiers
- 99900547837601842
- Language
- English
- Resource Type
- Journal article