Journal article
Persulfides: current knowledge and challenges in chemistry and chemical biology
Molecular bioSystems, Vol.11(7), pp.1775-1785
07/2015
Handle:
https://hdl.handle.net/2376/101288
PMCID: PMC4470748
PMID: 25969163
Abstract
Recent studies conducted in hydrogen sulfide (H2S) signaling have revealed potential importance of persulfides (RSSH) in redox biology. The inherent instability of RSSH makes these species difficult to study and sometimes controversial results are reported. In this review article we summarize known knowledge about both small molecule persulfides and protein persulfides. Their fundamental physical and chemical properties such as preparation/formation and reactivity are discussed. The biological implications of persulfides and their detection methods are also discussed.
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Details
- Title
- Persulfides: current knowledge and challenges in chemistry and chemical biology
- Creators
- Chung-Min Park - Department of Chemistry, Washington State University, Pullman, WA 99164, USA. mxian@wsu.eduLaksiri WeerasingheJacob J DayJon M FukutoMing Xian
- Publication Details
- Molecular bioSystems, Vol.11(7), pp.1775-1785
- Academic Unit
- Chemistry, Department of
- Publisher
- England
- Grant note
- R01GM088226 / NIGMS NIH HHS R01 GM088226 / NIGMS NIH HHS R01 HL116571 / NHLBI NIH HHS R01HL116571 / NHLBI NIH HHS
- Identifiers
- 99900546698601842
- Language
- English
- Resource Type
- Journal article