Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome P450 active sites

Journal article

Peer reviewed

Sean EKINS, Marcel J DE GROOT and Jeffrey P JONES

Drug metabolism and disposition, Vol.29(7), pp.936-944

2001

Handle:

https://hdl.handle.net/2376/114894

PMID: 11408357

Abstract

Fundamental and applied biological sciences. Psychology

Biological and medical sciences

Analytical, structural and metabolic biochemistry

Enzymes and enzyme inhibitors

Oxidoreductases

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Title: Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome P450 active sites
Creators: Sean EKINS - Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, United States
Marcel J DE GROOT - Molecular Informatics, Structure & Design, Pfizer Global Research and Development, Sandwich, Kent, United States
Jeffrey P JONES - Department of Chemistry, Washington State University, Pullman, Washington, United States
Publication Details: Drug metabolism and disposition, Vol.29(7), pp.936-944
Academic Unit: Chemistry, Department of
Publisher: American Society for Pharmacology and Experimental Therapeutics; Bethesda, MD
Identifiers: 99900548110001842
Language: English
Resource Type: Journal article