Journal article
Photoswitchable Nanoprobes Offer Unlimited Brightness in Frequency-Domain Imaging
Journal of the American Chemical Society, Vol.133(20), pp.7628-7631
05/25/2011
Handle:
https://hdl.handle.net/2376/106903
PMID: 21539363
Abstract
A single probe has limited brightness in time-domain imaging and such limitation frequently renders individual molecules undetectable in the presence of interference or complex cellular structures. However, a single photoswitchable probe produces a signal, which can be separated from interference or noise using photoswitching-enabled Fourier transformation (PFT). As a result, the light-modulated probes can be made super bright in the frequency domain simply by acquiring more cycles in the time domain.
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Details
- Title
- Photoswitchable Nanoprobes Offer Unlimited Brightness in Frequency-Domain Imaging
- Creators
- Alexander D.Q LiChuanlang ZhanDehong HuWei WanJiannian Yao
- Publication Details
- Journal of the American Chemical Society, Vol.133(20), pp.7628-7631
- Academic Unit
- Department of Chemistry
- Publisher
- American Chemical Society
- Identifiers
- 99900546979301842
- Language
- English
- Resource Type
- Journal article