Journal article
Photothermal-Switched Single-Atom Nanozyme Specificity for Pretreatment and Sensing
Small (Weinheim an der Bergstrasse, Germany), Vol.19(40), p.e2302929
10/01/2023
PMID: 37282757
Abstract
Various applications lead to the requirement of nanozymes with either specific activity or multiple enzyme-like activities. To this end, intelligent nanozymes with freely switching specificity abilities hold great promise to adapt to complicated and changeable practical conditions. Herein, a nitrogen-doped carbon-supported copper single-atom nanozyme (named Cu SA/NC) with switchable specificity is reported. Atomically dispersed active sites endow Cu SA/NC with specific peroxidase-like activity at room temperature. Furthermore, the intrinsic photothermal conversion ability of Cu SA/NC enables the specificity switch by additional laser irradiation, where photothermal-induced temperature elevation triggers the expression of oxidase-like and catalase-like activity of Cu SA/NC. For further applications in practice, a pretreatment-and-sensing integration kit (PSIK) is constructed, where Cu SA/NC can successively achieve sample pretreatment and sensitive detection by switching from multi-activity mode to specific-activity mode. This study sets the foundation for nanozymes with switchable specificity and broadens the application scope in point-of-care testing.
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Details
- Title
- Photothermal-Switched Single-Atom Nanozyme Specificity for Pretreatment and Sensing
- Creators
- Yu Wu - Central China Normal UniversityYinjun Tang - Central China Normal UniversityWeiqing Xu - Central China Normal UniversityRina Su - Central China Normal UniversityYing Qin - Central China Normal UniversityLei Jiao - Central China Normal UniversityHengjia Wang - Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol &, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R ChinaXiaowen Cui - Chinese Acad Sci, Beijing Synchrotron Radiat Facil, Beijing 100049, Peoples R ChinaLirong Zheng - Chinese Acad Sci, Beijing Synchrotron Radiat Facil, Beijing 100049, Peoples R ChinaCanglong Wang - Institute of Modern PhysicsLiuyong Hu - Wuhan Institute of TechnologyWenling Gu - Central China Normal UniversityDan Du - Washington State UniversityYuehe Lin - Washington State UniversityChengzhou Zhu - Central China Normal University
- Publication Details
- Small (Weinheim an der Bergstrasse, Germany), Vol.19(40), p.e2302929
- Academic Unit
- School of Mechanical and Materials Engineering
- Publisher
- Wiley
- Number of pages
- 9
- Grant note
- B17019 / Program of Introducing Talents of Discipline to Universities of China (111 program) 22074049; 22004042 / National Natural Science Foundation of China; National Natural Science Foundation of China (NSFC) CCNU22JC006 / Fundamental Research Funds for the Central Universities
- Identifiers
- 99901227642201842
- Language
- English
- Resource Type
- Journal article