Journal article
Pituitary adenylate cyclase activating polypeptide enhances rapid eye movement sleep in rats
Brain research, Vol.686(1), pp.23-28
1995
Handle:
https://hdl.handle.net/2376/104341
PMID: 7583267
Abstract
Pituitary adenylate cyclase activating polypeptide (PACAP), a member of the vasoactive intestinal polypeptide family, was tested for its effects on sleep in adult male Sprague-Dawley rats. PACAP was injected via intracerebro-ventricular cannula at light or dark onset; sleep and brain temperature (Tbr) were recorded for 12 h after injection. Rapid eye movement sleep (REMS) was significantly enhanced by 30 pmol, but not 3 or 300 pmol PACAP injected at dark onset. Non-REMS was not influenced by 3, 30, or 300 pmol PACAP Sleep and Tbr were not influenced by 3 or 30 pmol PACAP injected at light onset.
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Details
- Title
- Pituitary adenylate cyclase activating polypeptide enhances rapid eye movement sleep in rats
- Creators
- Jidong FangLinda PayneJames M Krueger
- Publication Details
- Brain research, Vol.686(1), pp.23-28
- Academic Unit
- Integrative Physiology and Neuroscience, Department of
- Publisher
- Elsevier B.V
- Identifiers
- 99900546746201842
- Language
- English
- Resource Type
- Journal article