Journal article
Pore size and pore volume effects on alumina and TCP ceramic scaffolds
Materials Science & Engineering C, Vol.23(4), pp.479-486
2003
Handle:
https://hdl.handle.net/2376/112011
Abstract
Controlled porosity alumina and β-tricalcium phosphate ceramic scaffolds with pore sizes in the range of 300–500 μm and pore volumes in the range of 25–45% were processed using the indirect fused deposition process. Samples having different pore sizes with constant volume fraction porosity and different volume fractions porosity with a constant pore size were fabricated to understand the influence of porosity parameters on mechanical and biological properties. In vitro cell proliferation studies were carried out with OPC1 human osteoblast cell line for 28 days with different scaffolds. Variation in pore size did not show any conclusive differences, but samples with higher volume fraction porosity showed some evidence of increased cell growth. Volume fraction porosity also showed a stronger influence on the mechanical properties under uniaxial compression loading. Compression strength dropped significantly for samples with higher volume fraction porosity, but changed marginally when only the pore size was varied.
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Details
- Title
- Pore size and pore volume effects on alumina and TCP ceramic scaffolds
- Creators
- Susmita Bose - School of Mechanical and Materials Engineering, Washington State University, P.O. Box 642920, Pullman, WA 99164 2920, USAJens Darsell - School of Mechanical and Materials Engineering, Washington State University, P.O. Box 642920, Pullman, WA 99164 2920, USAMartha Kintner - School of Biological Sciences and Molecular Biosciences, Washington State University, P.O. Box 644236, Pullman, WA 99164 4236, USAHoward Hosick - School of Biological Sciences and Molecular Biosciences, Washington State University, P.O. Box 644236, Pullman, WA 99164 4236, USAAmit Bandyopadhyay - School of Mechanical and Materials Engineering, Washington State University, P.O. Box 642920, Pullman, WA 99164 2920, USA
- Publication Details
- Materials Science & Engineering C, Vol.23(4), pp.479-486
- Academic Unit
- Mechanical and Materials Engineering, School of
- Publisher
- Elsevier B.V
- Identifiers
- 99900547650301842
- Language
- English
- Resource Type
- Journal article