Journal article
Prevalence of human-active and variant 1 strains of the tick-borne pathogen Anaplasma phagocytophilum in hosts and forests of eastern North America
The American journal of tropical medicine and hygiene, Vol.91(2), pp.302-309
08/2014
Handle:
https://hdl.handle.net/2376/109343
PMCID: PMC4125253
PMID: 24865688
Abstract
Anaplasmosis is an emerging infectious disease caused by infection with the bacterium Anaplasma phagocytophilum. In the eastern United States, A. phagocytophilum is transmitted to hosts through the bite of the blacklegged tick, Ixodes scapularis. We determined the realized reservoir competence of 14 species of common vertebrate hosts for ticks by establishing the probability that each species transmits two important strains of A. phagocytophilum (A. phagocytophilum human-active, which causes human cases, and A. phagocytophilum variant 1, which does not) to feeding larval ticks. We also sampled questing nymphal ticks from ∼ 150 sites in a single county over 2 years and sampled over 6 years at one location. White-footed mice (Peromyscus leucopus) and Eastern chipmunks (Tamias striatus) were the most competent reservoirs for infection with the A. phagocytophilum human-active strain. Across the county, prevalence in ticks for both strains together was 8.3%; ticks were more than two times as likely to be infected with A. phagocytophilum human-active as A. phagocytophilum variant 1.
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Details
- Title
- Prevalence of human-active and variant 1 strains of the tick-borne pathogen Anaplasma phagocytophilum in hosts and forests of eastern North America
- Creators
- Felicia Keesing - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York keesing@bard.eduDiana J McHenry - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New YorkMichelle Hersh - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New YorkMichael Tibbetts - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New YorkJesse L Brunner - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New YorkMary Killilea - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New YorkKathleen LoGiudice - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New YorkKenneth A Schmidt - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New YorkRichard S Ostfeld - Bard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York
- Publication Details
- The American journal of tropical medicine and hygiene, Vol.91(2), pp.302-309
- Academic Unit
- Biological Sciences, School of
- Publisher
- United States
- Identifiers
- 99900547381501842
- Language
- English
- Resource Type
- Journal article