Journal article
Proteinases of Trichomonas vaginalis: antibody response in patients with urogenital trichomoniasis
Parasitology, Vol.105(3), pp.387-391
12/1992
Handle:
https://hdl.handle.net/2376/109721
PMID: 1461679
Abstract
Immunoprecipitation combined with electrophoresis in gelatin-polyacrylamide gels was successfully used for detection of antibodies against numerous proteinases of Trichomonas vaginalis in infected patients. The method proved to be highly specific as anti-proteinase antibodies were absent in women with negative cultivation of T. vaginalis and no history of trichomoniasis. Sera of 71% and vaginal washes of 86% patients with trichomoniasis were positive for these antibodies. In vaginal washes, but not in sera, antibodies were partly complexed with proteinases, possibly of trichomonad origin. It was also shown that serum antibodies as well as local anti-proteinase antibodies persisted for weeks after patients had been cured.
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Details
- Title
- Proteinases of Trichomonas vaginalis: antibody response in patients with urogenital trichomoniasis
- Creators
- P Bózner - 1Institute of Microbiology and Immunology, Medical Faculty, Comenius University, Sasinkova 4, 811 08 Bratislava, CzechoslovakiaA Gombošová - 2Institute of Parasitology, Medical Faculty, Comenius University, Palisády 40, 811 06 Bratislava, CzechoslovakiaM valent - 2Institute of Parasitology, Medical Faculty, Comenius University, Palisády 40, 811 06 Bratislava, CzechoslovakiaP Demeš - 1Institute of Microbiology and Immunology, Medical Faculty, Comenius University, Sasinkova 4, 811 08 Bratislava, CzechoslovakiaJ. F Alderete - 3Department of Microbiology, The University of Texas Health Science Center, San Antonio, Texas 78284–7758, USA
- Publication Details
- Parasitology, Vol.105(3), pp.387-391
- Academic Unit
- Molecular Biosciences, School of
- Publisher
- Cambridge University Press; Cambridge, UK
- Number of pages
- 5
- Identifiers
- 99900547027001842
- Language
- English
- Resource Type
- Journal article