Journal article
RW-2018-Research Workshop: The Effect of Nutrition on Epigenetic Status, Growth, and Health
JPEN. Journal of parenteral and enteral nutrition, Vol.43(5), pp.627-637
07/2019
PMCID: PMC6625918
PMID: 30997688
Abstract
The goal of the 2018 American Society for Parenteral and Enteral Nutrition (ASPEN) Research Workshop was to explore the influence of nutrition and dietary exposure to xenobiotics on the epigenome during critical periods in development and how these exposures influence both disease incidence and severity transgenerationally. A growing compendium of research indicates that the incidence and severity of common and costly human diseases may be influenced by dietary exposures and deficiencies that modify the epigenome. The greatest periods of vulnerability to these exposures are the periconception period and early childhood. Xenobiotics in the food chain, protein malnutrition, and methyl donor deficiencies could have a profound bearing on the risk of developing heart disease, diabetes, obesity, hypertension, and mental illness over multiple generations. The financial impact and the life burden of these diseases are enormous. These and other aspects of nutrition, epigenetics, and health are explored in this research workshop.
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Details
- Title
- RW-2018-Research Workshop: The Effect of Nutrition on Epigenetic Status, Growth, and Health
- Creators
- Michael Skinner - Washington State University, Biological Sciences, School ofL. H. Lumey - Columbia University Irving Medical CenterTom P. Fleming - University of SouthamptonCarmen Sapienza - Temple UniversityCathrine Hoyo - North Carolina State UniversityLucia Aronica - Stanford UniversityJeff Thompson - Gundersen Health SystemPeter F. Nichol - University of Wisconsin–Madison
- Publication Details
- JPEN. Journal of parenteral and enteral nutrition, Vol.43(5), pp.627-637
- Academic Unit
- Biological Sciences, School of
- Publisher
- Wiley
- Number of pages
- 11
- Grant note
- R13HD094514 / Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) 701944 / European Union; European Union (EU)
- Identifiers
- 99901083540401842
- Language
- English
- Resource Type
- Journal article