Journal article
Randomized Trial of Behavioral Activation, Cognitive Therapy, and Antidepressant Medication in the Prevention of Relapse and Recurrence in Major Depression
Journal of consulting and clinical psychology, Vol.76(3), pp.468-477
06/2008
Handle:
https://hdl.handle.net/2376/100200
PMCID: PMC2648513
PMID: 18540740
Abstract
This study followed treatment responders from a randomized controlled trial of adults with major depression. Patients treated with medication but withdrawn onto pill-placebo had more relapse through one year of follow-up, compared to patients who received prior behavioral activation, prior cognitive therapy, or continued medication. Prior psychotherapy was also superior to medication withdrawal in the prevention of recurrence across the second year of follow-up. Specific comparisons indicated that patients previously exposed to cognitive therapy were significantly less likely to relapse following treatment termination than patients withdrawn from medication, and patients previously exposed to behavioral activation did almost as well relative to medication withdrawal at the level of a nonsignificant trend. Differences between behavioral activation and cognitive therapy were small in magnitude and not significantly different across the full two-year follow-up, and each was at least as efficacious as continuation medication. These findings suggest that behavioral activation may be nearly as enduring as cognitive therapy, and that both psychotherapies are less expensive and longer-lasting alternatives to medication in the treatment of depression.
Metrics
7 Record Views
Details
- Title
- Randomized Trial of Behavioral Activation, Cognitive Therapy, and Antidepressant Medication in the Prevention of Relapse and Recurrence in Major Depression
- Creators
- Keith S Dobson - University of CalgarySteven D Hollon - Vanderbilt UniversitySona Dimidjian - University of ColoradoKaren B Schmaling - University of North Carolina at CharlotteRobert J Kohlenberg - University of WashingtonRobert Gallop - West Chester UniversityShireen L Rizvi - National Center for PTSD, VA Boston Healthcare SystemJackie K Gollan - University of ChicagoDavid L Dunner - University of WashingtonNeil S Jacobson - University of Washington
- Publication Details
- Journal of consulting and clinical psychology, Vol.76(3), pp.468-477
- Academic Unit
- Psychology, Department of
- Identifiers
- 99900546692801842
- Language
- English
- Resource Type
- Journal article